General Cell Lines and Cell Cultures
ATCC Myceliophthora thermophila
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.
Biochain Institute Inc Matched Pair - DNA - Human Primary and Metastatic Tumor Tissue: Kidney, 2x10 ug/PK
BioChain's human DNA matched pair products include: Primary Pair (PP), Primary and Metastasis Pair (PM). PP consists of DNA prepared from primary tumor and its adjacent normal tissue; PM consists of DNA prepared from primary tumor and corresponding ponding metastatic tumor. Genomic DNA in each pair is prepared from the same donor. This product line is designed foridentifying tumor-specific genes and tumor metastatic genes.
Eurofins Discoverx PathHunter CHO-K1 GPR143 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0362C2A)
The PathHunter GPR143 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR143 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR143 and EA-tagged β-Arrestin-2. Activation of GPR143 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 cyno GPR120 β-Arrestin Cell Line, 2 vials. (93-1029C2)
The PathHunter cyno GPR120 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. free fatty acids) based activation of cyno GPR120 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged cyno GPR120 and EA-tagged β-Arrestin-2. Activation of cyno GPR120 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Cynomolgus monkey version of the protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx Ready-to-Assay GnRH Gonadotropin-Releasing Receptor Frozen Cells, 2 Vials of Cells. (HTS027RTA)
The Ready-to-Assay GnRH Gonadotropin-Releasing Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. gonadotropin-releasing hormone) based activation of GNRHR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses GNRHR alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of GNRHR, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
ATCC HCT116-SLC10A4-KO-c8; Colorectal carcinoma; Human (Homo sapiens)
The HCT116-SLC10A4-KO-c8 cell line contains a -13 deletion in SLC10A4 gene and combined with the parental cell line and other HCT116 derivatives can be used in cancer drug screening.
ATCC HCT116-MTCH1-KO-c7; Colorectal carcinoma; Human (Homo sapiens)
The HCT116-MTCH1-KO-c7 cell line contains a -7 deletion in MTCH1 gene and combined with the parental cell line and other HCT116 derivatives can be used in cancer drug screening.
ATCC Murine adenovirus 1; Strain: FL
Murine adenovirus 1 strain FL is propagated in BALB/3T3 clone A31 cells (ATCC CCL-163). This strain was isolated from the spleen pool of mice infected with the Friend leukemia virus. The strain has applications in immune system disorder research.
Biochain Institute Inc Matched Pair - Frozen Tissue Section - Human Primary and Matched Metastatic Tumor (PM): Lung, 5 x2 slides /PK
BioChain's tissue products are based on the sample repository network established following the ethical standard and IRB-approved procedures. During the collection, the excised tissues are immediately put into liquid nitrogen and then identified by a board-licensed pathologist. Patient demographic and disease related history data are available. Human frozen tissue section matched pair products include: Primary Pair (PP), Primary and Metastatic Pair (PM). PP consists of frozen tissue sections of primary tumor and its adjacent normal tissue; PM consists of frozen tissue sections of primary tumor and corresponding metastatic tumor. Frozen tissue sections in each pair are prepared from the same donor. This product line is ideal for localization of tumor-specific genes and tumor metastatic genes.
ATCC Influenza A (H3N2); A/Hong Kong/4801/2014 (H3N2)
Influenza A virus (H3N2) strain A/Hong Kong/4801/2014 is propagated in SPF chicken embryonated eggs. This strain was isolated in 2014 from a human in Hong Kong and was deposited by The Francis Crick Institute. It has applications in respiratory disease research, assay development, and vaccine development.
Montana Molecular Borealis Arrestin MOR Assay - 10mL
Measure arrestin signaling kinetics in real time with the live cell, fluorescent Borealis arrestin - Mu Opioid receptor (MOR) assay. Add the unmodified MOR and Borealis sensor to cells and measure robust signals the next day on an automated plate reader or fluorescence imaging system. This assay is genetically encoded and packaged in BacMam for efficient transduction in most cell types - including uniform and near 100% efficiency in HEK293 cells as well as expression in many primary or iPSC-derived cells. The kit includes the arrestin sensor BacMam, MOR BacMam, GRK2 BacMam, 500mM sodium butyrate in H2O, and a positive control receptor and agonist (AT1R BacMam and 5mM Angiotensin II in H2O). Borealis kits for several other receptors are also available, and larger-sized kits are available on request. Other Montana Molecular tools including the cADDis cAMP sensor can be used alongside this assay.
![PBL Assay Science iLite Human Type I Interferon (IFN) Responsive Cells [2.5 mL/vial]](https://assets.fishersci.com/TFS-Assets/CCG/product-images/501538076.jpg-250.jpg)
PBL Assay Science iLite Human Type I Interferon (IFN) Responsive Cells [2.5 mL/vial]
iLite Human Type I Interferon Responsive Cells are sold by PBL Assay Science (Catalog #51100-7) for research use only (RUO) and packaged in 2.5 mL/vial. These engineered cells are provided as assay ready frozen cells. The cell line is highly specific for its target due to cell engineering using a target-specific reporter gene construct.
STEMCELL Technologies Human Bone Marrow Mononuclear Cells, Frozen, Size: 1 x 10^8 cells
Primary bone marrow mononuclear cells (a.k.a. BM MNCs or BMNCs) are a heterogeneous population that includes hematopoietic lineage cells such as lymphocytes, monocytes, stem cells, and progenitor cells as well as mesenchymal stromal cells. Mononuclear cells are isolated from human adult bone marrow using density gradient separation. Heparin is added to the bone marrow upon collection as an anticoagulant.Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols.Certain products are only available in select territories. Please contact your local Sales representative or Product & Scientific Support at techsupport@stemcell.com for further information.
Biochain Institute Inc Frozen Tissue Section - Human Adult Normal: Brain: Brain Stem, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Eurofins Discoverx InCELL Hunter HEK 293 BRD2(1,2) Bromodomain Cell Line, 2 vials. (96-0049C1)
The InCELL Hunter HEK 293 BRD2(1,2) Bromodomain Cell Line is a stable, engineered cell line for use in studying small molecule drug candidates that engage with regulators of epigenetics pathways. This cell line enables assessment of compound-engagement-based stabilization of BRD2(1,2) via detection of BRD2(1,2) levels. This product uses EFC technology. The cell line included overexpresses BRD2(1,2) target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/epigenetics.